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Nathan Stoll :

I’ve been comforted by the realization that Google benefits by my departure to tackle new endeavors. Great companies like Goldman Sachs, McKinsey & Company, Procter & Gamble, and GE all consistently turn out leaders in their fields; their employee departures complement the mother ship by spreading the culture and working ethos. Google has many more fine minds joining than it has leaving, and is training them to be technology-focused leaders with a passion for building great consumer focused services.

corporate economy idea

Snorting a Brain Chemical Could Replace Sleep

Snorting a Brain Chemical Could Replace Sleep

In what sounds like a dream for millions of tired coffee drinkers, Darpa-funded scientists might have found a drug that will eliminate sleepiness.

A nasal spray containing a naturally occurring brain hormone called orexin A reversed the effects of sleep deprivation in monkeys, allowing them to perform like well-rested monkeys on cognitive tests. The discovery’s first application will probably be in treatment of the severe sleep disorder narcolepsy.

The treatment is “a totally new route for increasing arousal, and the new study shows it to be relatively benign,” said Jerome Siegel, a professor of psychiatry at UCLA and a co-author of the paper. “It reduces sleepiness without causing edginess.”

Orexin A is a promising candidate to become a “sleep replacement” drug. For decades, stimulants have been used to combat sleepiness, but they can be addictive and often have side effects, including raising blood pressure or causing mood swings. The military, for example, administers amphetamines to pilots flying long distances, and has funded research into new drugs like the stimulant modafinil (.pdf) and orexin A in an effort to help troops stay awake with the fewest side effects.

sleep sociology stimulant


Back in October, Getting Things Done author David Allen gave a talk at Google entitled “GTD and the Two Keys to Sustaining a Healthy Life and Workstyle,” and now the video clip’s available on YouTube. While this is definitely a worthy watch for GTD followers (or those who aspire to be), if you don’t have a spare 45 minutes, the two keys are:

  • Control: Conscious focused engagement, aware of all options at any one time and place
  • Perspective: aligned and clear about decisions, directions, and priorities.

All in all a nice GTD primer right from the horse’s mouth. Thanks, Steve!


David Allen on "Knowledge Work Athletics" [Video]

Originally from Lifehacker by Gina Trapani

Skater Dater 1965 - vintage short film

Detailed satellite photo of the northern polar ice cap showing that for the first time in recorded history, the Northwest passage (the orange line) is open to sea traffic. The passage was a subject of intense interest to the European powers from the late 1400s, who wanted to find a way to Asia by boat that didn’t involve sailing around Africa. (via ben)

(link)

Detailed satellite photo of the northern polar ice cap showing…

Originally from kottke.org

Guerrilla Gardening: A Manualfesto

Maya Khankhoje in Rabble Book Reviews:

Screenhunter_10_sep_18_1724Guerrilla gardening can be summarily defined as gardening in public urban spaces with or without permission. Gardening by the citizens, that is, by urban guerrillas intent, not on destroying the status quo as such but on restoring the web of life that the status quo has been destroying so wantonly. Why do these citizens feel such a sense of urgency? Consider the following:

The earth is cultivated more than ever before…swamps are drying up and cities are springing up at an unprecedented scale. We have become a burden to our planet. Resources are becoming scarce and soon nature will no longer be able to satisfy our needs.

This pressing concern was voiced by Quintus Septimus Tertullian more than 2,200 years ago. This is the very same concern that has spurred urban guerrillas of a gentler, albeit no less radical bend of mind than armed guerrillas, to engage in urban gardening tactics, risking fines and imprisonment. These include fly-by-night plantings in urban wastelands, lobbing “seed grenades” into fenced-off empty lots, planting trees in the middle of nowhere, covering traffic circles with native ground cover, sowing edible plants in school-yards, draping lamp posts with decorative creepers, developing community gardens and empowering disaffected youth by reintroducing them to the joys of dirtying one’s hands in the soil. The list is as boundless as any warrior’s imagination.

More here.

Guerrilla Gardening: A Manualfesto

Originally from 3quarksdaily by Abbas Raza

Steven Johnson in Discover Magazine:

LaughterkidsWe take it for granted that tickling causes laughter and that one person’s laughter will easily “infect” other people within earshot. Even a child knows these things. (Tickling and contagious laughter are two of the distinguishing characteristics of childhood.) But when you think about them from a distance, they are strange conventions. We can understand readily enough why natural selection would have implanted the fight-or-flight response in us or endowed us with a sex drive. But the tendency to laugh when others laugh in our presence or to laugh when someone strokes our belly with a feather—what’s the evolutionary advantage of that?

There is a long, semi-illustrious history of scholarly investigation into the nature of humor, from Freud’s Jokes and Their Relation to the Unconscious, which may well be the least funny book about humor ever written, to a British research group who claimed they had determined the world’s funniest joke. Despite the fact that the researchers sampled a massive international audience in making this judgment, the winning joke revolved around New Jersey residents: A couple of New Jersey hunters are out in the woods when one of them falls to the ground. He doesn’t seem to be breathing; his eyes are rolled back in his head. The other guy whips out his cell phone and calls the emergency service. He gasps to the operator: “My friend is dead! What can I do?” The operator says: “Take it easy. I can help. First, let’s make sure he’s dead.” There is silence, then a shot is heard. The guy’s voice comes back on the line. He says, “OK, now what?”

This joke illustrates the notion of controlled incongruity: You’re expecting x, and you get y.

More here.

What’s the evolutionary advantage of laughing when someone strokes our belly with a feather?

Originally from 3quarksdaily by Abbas Raza

Manic mood swings can destroy grey matter

From Nature:

Brain Grey matter in the brains of people with bipolar disorder is destroyed with each manic or depressive episode. This was the finding of an MRI study of 21 patients with bipolar disorder, a mental illness marked by successive episodes of mania followed by deep depression. The patients’ brains were scanned at either end of a four-year period, during which time each patient had at least one episode and some as many as six. In all cases, the amount of grey matter in the temporal lobe and the cerebellum decreased compared to the grey matter in control subjects. These areas of the brain are associated with memory and coordination.

Patients that had suffered more episodes over the four years had the most marked difference in the amount of grey matter that had disappeared.

More here.

Manic mood swings can destroy grey matter

Originally from 3quarksdaily by Azra Raza

How to Give a Back Massage - Video | eHow.com

Singing Tesla Coil: video

Xeni Jardin:
Snip:

This is a solid-state Tesla coil. The primary runs at its resonant frequency in the 41 KHz range, and is modulated from the control unit in order to generate the tones you hear.

What’s not immediately obvious in this video is how loud this is. Many people were covering their ears, dogs were barking. In the sections where the crowd is cheering and the coils is starting and stopping, you can hear the the crowd is drowned out by the coil when it’s firing.

Video Link. (Thanks, Robert!)

Singing Tesla Coil: video

Originally from Boing Boing by Xeni Jardin



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